LM1 SUMMARY 24

CONTENTS OF THE SPECIAL "L&M-REGENLAB" ISSUE

AUTOLOGOUS CELLULAR REGENERATIVE MEDICINE

AT THE FOREFRONT OF AESTHETIC AND ANTI-AGING MEDICINE

EDITORIALS

1. Autologous cellular regenerative medicine in medicine and surgery today. The rise of platelet-rich plasma (PRP) in regenerative medicine: a promising horizon.
Prof. Jean-Paul MENINGAUD, Head of the Plastic, Reconstructive and Maxillofacial Surgery Department. Hôpital Henri Mondor, Créteil, France. Scientific Director of Look et Medecine. President of the AIME congress. www.meningaud.com

2. Clinical research and industrial development of autologous PRP by REGENLAB. Autologous PRP or "The Fairy Plate" in the magical land of regenerative autologous cellular medicine.
Antoine TURZI, CEO of Laboratoire Regenlab.

BASIC AND CLINICAL RESEARCH ON AUTOLOGOUS PRP AND MEDICAL APPLICATIONS

II.1 Multidisciplinary clinical research

II.1.1. Clinical research in human practice

RegenPRP®, a standardized autologous platelet concentrate: 10 years of clinical research and practice.
Pr Barbara HERSANT MD, PhD. Department of Plastic, Reconstructive and Maxillofacial Surgery, Hôpital Henri Mondor, Créteil, France.

II.1.2. Basic experimental research on PRP and angiogenesis, a key stage in tissue regeneration

Angiogenesis, a key step in tissue regeneration, is modulated by platelets.
Sarah BERNDT MD, Gilles CARPENTIER MD, Axel TOLLANCE MD, Antoine TURZI CEO RegenLab

II.1.3. Basic experimental research on PRP and myogenesis for cell therapy of musculoskeletal disorders

Evaluation of Platelet Rich Plasma (PRP) as an Alternative to Fetal Calf Serum (FBS) in Human Myoblast Expansion: an In Vitro Protocol
Axel TOLLANCE, Diego MICHEL, Alexandre PROLA, Axelle BOUCHE, Antoine TURZI, Didier HANNOUCHE, Thomas LAUMONIER, Sarah BERNDT.

II.2 PRP in rheumatology

II.2.1. RegenPRP®, for gonarthrosis. From HA viscosupplementation to combination with PRP for the treatment of gonarthrosis: the Cellular Matrix® revolution.
Philippe ADAM MD, Marine DELCROS, MD - Regen Lab.

II.2.2.Autologous platelet-rich plasma (PRP) as a treatment for osteoarthritis of the knee.
Solange VISCHER, Senior Scientific Advisor, Regen Lab SA, Antoine TURZI, CEO, RegenLab SA.

II.2.3 Platelet-rich plasma and symptomatic gonarthrosis. Summary of international recommendations.
Marine DELCROS, MD. - Regen Lab.

II.2.2. RegenPRP® for calcaneal tendinopathy

Platelet Rich Plasma and calcaneal tendinopathy
Marine DELCROS, MD.

II.3. PRP in dermatology

Platelet-rich plasma as a safe and effective autologous treatment for chronic wound healing.
Solange VISCHER, Senior Scientific Advisor, RegenLab, Antoine TURZI, CEO RegenLab.

Correction of age-related changes with autologous thrombin-activated Platelet Rich Plasma and hyaluronic acid in combination with radiofrequency microneedling equipment.
Inna SHARYPOVA, M.D., Ph.D., Dermatologist, Kristel Medical Research Center, Milan, Italy. Andrey ALENICHEV, M.D., Ph.D., Dermatologist, Kristel Medical Research Center, Milan, Italy.,Daniil FEDOROV, Research Analyst, Kristel Medical Research Center, Milan, Italy. 3

II.4. PRP in gynecology

II.4.1. Treatment of post-cancer genitourinary syndrome
Vaginal health in women who have had breast cancer.
Dana SAWAN MD, Barbara HERSANT, MD, PhD.

II.5. PRP and alopecia

II.5.1. Effective hair restoration in patients with baldness using a comprehensive bio-revitalization treatment. A preliminary prospective medical study.
Pilar REYES MD, Gustavo H. LEIBASCHOFF, MD.

II.5.2. Motivation for studying the effect of Platelet Rich Plasma (PRP) on post-chemotherapy alopecia (PCA) and post-endocrine therapy alopecia (PEA).
Leore LAVIN MS, Alex PAN MD, Anthony ROSSI MD, Antoine TURZI, CEO RegenLab

III. INTERNATIONAL STANDARDS FOR AUTOLOGOUS PRP AND PRODUCTION DEVICES

III.1.1. Good practices for the preparation of Autologous Platelet Rich Plasma (PRP-A) from the recipient's blood.

International standards: May 26, 2024. A last look at MDD 97/43. Welcome to MDR 2017/745.
Daphné V. DIERMAN, PhD Pharmacist, Antoine TURZI, CEO RegenLab.

III.1.2 Patents for RegenLab's autologous PRP.

Overview of RegenLab's patented technologies.
Andreas Pigni, Legal Affairs, RegenLab AG